Evidence-based peptide reference · updated April 2026

The clinical source of truth for peptide therapy.

33 peptides, 20 clinics, live FDA tracking, and community signal — synthesized for patients, clinicians, and researchers. Medical-reviewer signed.

Reviewed by Marko Maal, MSc PharmacyUpdated May 17, 202646 articles · 4 cornerstonesEvidence-tier labeled

Direct answers

TL;DRLive · 301 threads in 7 days

What is the peptide community actually discussing this week?

Across the last 7 days, 301 new community threads. Tirzepatide leads the conversation, with Semaglutide and Retatrutide close behind — and personal experience and dosing & protocols are the dominant themes right now. This is editorially classified community signal, refreshed continuously — trend visibility, not medical advice.

See the community signal report
Pillar guide12 min read · Reviewed Apr 2026

What peptides are, what they aren't, and how they actually work.

The complete, medical-reviewer-signed beginner's guide. Mechanism, evidence tiers, dosing, legal status, and how to separate real therapeutics from biohacker hype.

Short chains of 2–50 amino acids that act as biological signaling molecules. They tell cells what to do — release growth hormone, migrate to damaged tissue, modulate hunger. Some are FDA-approved (semaglutide, tirzepatide). Some are compounded (BPC-157). Some are research-only (KPV, MOTS-c).

Read the full guide

Covers: 33 peptides · every major pillar · all 50 states

Start with a goal

8 pillars · goal-based navigation

Most searched peptides

All peptides →

Ranked by 30-day query volume across Google + LLM citations

Find a clinic

Telehealth · all 50 states

Telehealth coverage across all 50 states + 20+ verified providers

View all 50 states →

Comparison pages

All comparisons →

Side-by-side mechanism, dosing, evidence

Last 24 hours on Reddit

13 posts · trend visibility, not medical advice
Experience · 5Dosing · 5Question · 3
  1. 01
    GH peptides barely move body composition, and nobody selling them tells you
    r/PeptidesExperienceSermorelin · CJC-1295 / Ipamorelin · MK-677 (Ibutamoren)9h ago
  2. 02
    Experiences with sermorelin as a weight loss peptide
    r/PeptidesExperienceSermorelin · Semaglutide9h ago
  3. 03
    23kg lost since September
    r/MounjaroExperienceTirzepatide13h ago
  4. 04
    DSIP and Epitalon making sleep worse
    r/PeptidesDosingEpitalon · DSIP4h ago

Source: public Reddit, classified on ingest. Surfacing reflects topic relevance, not endorsement. Full feed →

From the data

All reports →

What the peptide community is actually discussing — analyzed from thousands of Reddit posts. Community signal, not clinical evidence.

✦ Data report1,857 posts analyzed

What 1,857 peptide Reddit posts reveal about the community (2026)

We analyzed 1,857 peptide-related Reddit posts. GLP-1s (tirzepatide, retatrutide, semaglutide) dominate ~52% of mentions. The most common topic isn't results — it's dosing & titration (41% of posts), followed by sourcing and side effects. This is community-signal data, not clinical evidence.

Read the analysis →

Community signal · live

Open full feed →

Synthesized across Reddit, Bluesky, PubMed, and FDA — refreshed on cron, latest first.

Live
reddit · Update: Selank and peptides to help with anxiety
updated 23m ago · 0 sources/24h

Items / 24h

0

live

Reddit posts

2,477

tracked

Research

87

PubMed papers

FDA alerts

0

this period

What's published

Live counts · auto-updated

Peptides covered

33

Clinics tracked

20

Supporting articles

160

Comparison pages

12

Goal pillars

9

Legal guides

0

Evidence tiers

Every claim is tagged Tier 1–5 — RCT to anecdotal — so you can read intensity and confidence at a glance. No hype.

Protocol logs

Structured submissions, not freeform forum chatter. Dose × duration × delivery × result. Aggregations are reviewed before they're surfaced.

Lab transparency

Vendor products go to ISO-17025 labs. Results published whether or not the vendor likes the outcome.